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Prostaglandin D2-d4 
Prostaglandin D2-d4
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英文名稱(chēng) : Prostaglandin D2-d4
貨號(hào) : EY-01Y14189
CAS : 211105-29-2
含量 : >99.00%
規(guī)格 : 25 μg、50 μg、100 μg
品牌 : 上海一研
價(jià)格 :
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產(chǎn)品屬性:


產(chǎn)品名稱(chēng)

Prostaglandin D2-d4

規(guī)格

25 μg、50 μg、100 μg

貨號(hào)

EY-01Y14189

Cas No.: 211105-29-2

別名: N/A

化學(xué)名: N/A

分子式: C20H28D4O5
GC47988.png
分子量: 356.5

溶解度: DMF: >100 mg/ml (from PGD2),DMSO: >50 mg/ml (from PGD2),Ethanol: >75 mg/ml (from PGD2),PBS pH 7.2: >5 mg/ml (from PGD2)

儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping ConditionEvaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

產(chǎn)品描述:


Prostaglandin D2-d4 (PGD2-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGD2 by GC- or LC-mass spectrometry. PGD2 is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of PGD2, which causes vasodilation, flushing, hypotension, and syncopal episodes. PGD2 is also produced in the brain via an alternative pathway involving a soluble, secreted PGD-synthase also known as β-trace.2,3 In the brain, PGD2 produces normal physiological sleep and lowering of body temperature. Further pharmacological actions include inhibition of platelet aggregation and relaxation of vascular smooth muscle. PGD2 inhibits human ovarian tumor cell proliferation with an IC50 of 6.8 μM.N/A
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