產品屬性:
產品名稱 | RAF mutant-IN-1 |
規(guī)格 | 100mg、250mg、500mg |
貨號 | EY-01Y12758 |
Cas No.: 2340020-82-6
別名: N/A
化學名: N/A
分子式: C23H18Cl3FN6O2S
分子量: 567.85
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively[1].
C-RAF 340D/Y341D|21 nM (IC50)|B-RafV600E|30 nM (IC50)|BRAFWT|392 nM (IC50)
[1]. BAE, In Hwan, et al. Title of Invention: THIENO[3,2-d]PYRIMIDINE COMPOUND HA VING INHIBITORY ACTIVITY FOR PROTEIN KINASE. WO2019107987A1.
特別提醒公司產品僅供科研使用