產(chǎn)品屬性:
產(chǎn)品名稱 | Piloty's Acid |
規(guī)格 | 500mg、1g、5g、10g |
貨號(hào) | EY-01Y10854 |
Cas No.: 599-71-3
別名: N/A
化學(xué)名: N/A
分子式: C6H7NO3S
分子量: 173.2
溶解度: DMF: 30 mg/ml,DMSO: 20 mg/ml,Ethanol: 30 mg/ml,PBS (pH7.2): 2 mg/ml
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Nitric Oxide (NO) is a free radical gas that is involved in a variety of biological processes including regulation vascular tone, neuronal signaling, and host defense. Nitroxyl (HNO) is the one electron reduced form of nitric oxide. Piloty's acid is one of the best known and most widely used HNO donors. Under basic conditions Piloty's acid decomposes to HNO and benzenesulfinate anion. The rate of HNO release at pH 7 is very slow (t? = 5,500 minutes) making its use most effective above pH 8.0. The half-life of Piloty's acid decreases with an increase in pH to 561, 90, and 33 minutes at pH 8.0, 9.0, and 10.0, respectively. Piloty's acid also inhibits yeast aldehyde dehydrogenase with an IC50 or 48 μM.
特別提醒公司產(chǎn)品僅供科研使用