產(chǎn)品屬性:
產(chǎn)品名稱 | Pterosin B |
規(guī)格 | 10mM*1mL in DMSO、1mg、5mg、10mg、50mg、100mg |
貨號 | EY-01Y10476 |
Cas No.: 34175-96-7
別名: N/A
化學名: N/A
分子式: C14H18O2
分子量: 218.29
溶解度: DMSO: 250 mg/mL (1145.27 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Pterosin B, a indanone found in bracken fern (Pteridium aquilinum), is an inhibitor of salt-inducible kinase 3 (Sik3) signaling. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3[1][2].[1]. Hannah R.Dexter, et al. A concise stereoselective synthesis of pterosin B. Tetrahedron Letters, Volume 59, Issue 49, 5 December 2018, Pages 4323-4325.
[2]. Yahara Y, et al. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3. Nat Commun. 2016 Mar 24;7:10959.
特別提醒公司產(chǎn)品僅供科研使用